Proteins and Brain Networks in Atypical Alzheimer’s Disease
The purpose of this research study is to find out how Alzheimer’s disease, including less common forms of it, affects brain networks, how the Alzheimer’s protein tau spreads in the brain, and how tau and disrupted brain networks relate to your abilities on tests of memory and thinking. Brain networks can be measured with magnetic resonance imaging (MRI). Tau is a protein that builds up abnormally in Alzheimer’s disease and can be measured with positron emission tomography (PET) scanning. Our study combines all of these procedures, meaning that our participants have a total of three visits; an initial screening, an MRI visit with cognitive testing, and a PET visit.